Background: : Laparoscopic hysterectomy is a standard
gynecological surgical treatment used to treat a variety of
gynecological conditions. We aimed to evaluate the efficacy and
safety of adding two different doses of intraperitoneal
dexamethasone to bupivacaine versus bupivacaine alone for
postoperative analgesia after laparoscopic hysterectomy.
Methods: This randomized trial included 87 females who were
scheduled for elective laparoscopic hysterectomy. Patients were
randomly allocated into three equal groups: group I; received
bupivacaine 100 ml 0.25% + 5 ml normal saline, group II;
received bupivacaine 100 ml 0.25% + 4 mg dexamethasone (1
ml) + saline 4 ml, and group III; received bupivacaine 100 ml
0.25% + 8 mg dexamethasone (2 ml) + saline 3 ml. All patients
were monitored with a 5-lead electrocardiogram, pulse oximeter,
and non-invasive automated blood pressure as they arrived in the
operation room. Results: Time of the 1st rescue analgesic
requirement was significantly delayed in group III compared to
group I and group II (P