Background: Acute respiratory failure is potentially life
threatening. It does not require immediate intubation and the
likelihood of a positive result hinges on the doctor's capacity to
promptly identify the syndrome and implement suitable actions
to aid and recover respiratory system function. Objectives: The
research aimed to contrast the use of high-flow nasal cannula and
non-invasive mechanical ventilation in treating patients
experiencing acute respiratory failure. Study design: A metaanalysis study adhering to the PRISMA (Preferred Reporting
Items for Systematic Reviews and Meta-Analysis) guidelineswas conducted. Methods: Online databases (PubMed, EMBASE,
Biomed, and the Cochrane Central Register of Controlled trials)-
were utilized to detect all published randomized studies that
compare the impact of high-flow nasal cannula with non-invasive
ventilation in patients dealing with acute respiratory failure