أحمد مصطفي إبراهيم أبو سقايه
أستاذ مساعد
Pregabalin as Alternative to Epidural Blood Patch in Treatment of Postdural Puncture Headache: A Randomized Controlled Clinical Trial
• 2024
معلومات البحث
المؤلفون
Nahed Fouad Abo-Elmaety, Neveen Kohaf, Hany Bauiomy, Ahmed Abosakaya
الكلمات المفتاحية
Not Available
المجلة العلمية
Not Available
الناشر
Not Available
المجلد
Not Available
العدد
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الصفحات
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publication.type
Local
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Background
Postdural puncture headache (PDPH) commonly arises following a lumbar puncture. It is typically managed through conservative measures or an epidural blood patch (EBP), but each has limitations. This trial aimed to compare the efficacy and safety of pregabalin versus EBP in the management of PDPH.
Methods
This randomized controlled trial was conducted on 75 cases with confirmed diagnosis of PDPH. Patients were equally randomized into three groups: Group A (pregabalin group) received oral pregabalin treatment administered at 150 mg daily, with 75 mg given every 12 hours. Group B (EBP group) received EBP and Group C (control group) received conservative treatment.
Results
Complete relief of headache was experienced by 13 (52%) patients in group A, 18 (72%) patients in group B, and 5 (20%) patients in group C, with significant distinctions observed among the examined groups (P
Postdural puncture headache (PDPH) commonly arises following a lumbar puncture. It is typically managed through conservative measures or an epidural blood patch (EBP), but each has limitations. This trial aimed to compare the efficacy and safety of pregabalin versus EBP in the management of PDPH.
Methods
This randomized controlled trial was conducted on 75 cases with confirmed diagnosis of PDPH. Patients were equally randomized into three groups: Group A (pregabalin group) received oral pregabalin treatment administered at 150 mg daily, with 75 mg given every 12 hours. Group B (EBP group) received EBP and Group C (control group) received conservative treatment.
Results
Complete relief of headache was experienced by 13 (52%) patients in group A, 18 (72%) patients in group B, and 5 (20%) patients in group C, with significant distinctions observed among the examined groups (P