In this paper, the parameters of the extended odd Weibull exponential distribution are estimated under progressive type-II censoring scheme with random removal. The model parameters are estimated using the maximum product spacing and maximum likelihood estimation methods. Further, we explore the asymptotic confidence intervals and bootstrap confidence intervals for the model parameters. Monte Carlo simulations are performed to compare between the proposed estimation methods under progressive type-II censoring scheme. An empirical study using two real datasets form engineering and medicine fields to validate the introduced methods of inference. Based on our study, we can conclude that the maximum product of spacing method outperforms the maximum likelihood method for estimating the extended odd Weibull exponential (EOWE) parameters under a progressive type-II censoring scheme in both numerical and empirical cases.