This study was carried out to assess the efficacy of some volatile oils and Varroazal® for controlling Varroa mites (Varroa destructor) in honey bee colonies (Apis mellifera L.) during the period from 1st of July till the end of October 2015 and 2016 in Qalubia governorate, Egypt. Randomized complete block design was applied at this study. The apiary was divided into 7 treatments (3 colonies / group). The treatments were the use of oils of clove, peppermint, thymol, camphor, Varroazal®, mavric and control (without treatment). Mean No. of fallen varroa mites before treatment ranged between 5-15 mite/colony during the two experimental months 2015 and 2016. Data indicated that the most effective treatments were mavric and Varroazal®, while the lowest effective one was the treatment of camphor oil, during the seasons of study.