Background: Heart failure (HF) is a major public health concern
globally and in Egypt. Understanding the prevalence of different
etiologies and management practices in Egyptian HF patients is
crucial for targeted healthcare strategies. This study aimed to
assess the prevalence of different etiologies and management
practices in a contemporary cohort of Egyptian patients with HF.
Methods: This cross-sectional, multi-center observational study
was conducted over 12 months at Agouza Police Hospital and
Benha University Hospital, including 503 Egyptian HF patients.
Data collection involved patient interviews, clinical
examinations, and reviews of medical records and diagnostic
tests. Results: This study comprised 70% males and 30%
females, with an average age of 61 years. The primary etiologies
of HF were ischemic heart disease (68.8%), hypertension (23%),
and valvular heart disease (5.2%). The mean left ventricular
ejection fraction (LVEF) was 45% ± 12. Pharmacological
therapy included ACEIs/ARBs (79.9%), ARNI (10.9%), Betablockers (95.4%), MRAs (86.8%) and SGLT2 inhibitors
(84.9%). A total of 94.4% of patients exhibited ECG
abnormalities, and 34.3% had abnormal chest X-rays.
Conclusion: Ischemic heart disease and hypertension constituted
the most common causes of HF. A significant percentage of
patients received ACEIs/ARBs, Beta-blockers, MRAs, and
SGLT2 inhibitors. The study highlights the need for tailored
management strategies in the Egyptian context, considering the
specific etiological patterns and treatment practices observed.