The global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) generated a pandemic which severely impacted on care delivery worldwide. Aim of the work: To assess the correlation between CORADS score and different CBC indices and the sensitivity of CORADs score compared to lymphopenia and neutrophil/ lymphocyte ratio in diagnosing patients with COVID- 19. Patients and methods :This study is a retrospective data review study done 106 patients who were visiting the emergency room at Benha University hospital for assessment of symptoms for the possibility of COVID 19.Results: Symptoms were variable ; the most common was fever (92.5%), mean total leucocytic count (TLC) 7.5±3.4 (10*3/UL); neutrophil count 5.5±3.3 (10*3/UL), lymphocytic count was 1.42 ± 0.77.CT scan done to all patients where GGO was the most common pattern. CORAD score was ranging from 0 to 5 with mean 3.96±1.59, There was no correlation between CORAD score and different CBC parameters; CORAD scores ≥ 4 had a sensitivity of 71% while CORAD 5 has a sensitivity of 60% in diagnosis. Lymphopenia 2.4. Conclusion: CORAD score and lymphopenia are rapid and valuable tools in diagnosis of COVID 19. CORAD has a sensitivity 60 to 71% according to the cut off used while lymphopenia has a sensitivity 40 to 82%, neutrophil/ lymphocyte ratio 61 to 68%.