Background: E-learning platforms has received a great deal of attention from the educators and researchers. The use of E-learning in the field of education has become popular during COVID-19 outbreak. However, there are many challenges faced by educators and students which affect their intention to use and satisfaction. Aim: Assess factors affecting of electronic learning platform using as perceived by nursing educators and students and its relation to nursing students' satisfaction. Design: A descriptive correlational design was utilized. Setting: This study was conducted at the Faculty of Nursing, Benha University. Subjects: Sample of 93 nursing educators (Lecturers, Assistant professors and Professors) and stratified random sample of 1008 of nursing students from four academic years (2021/2022). Tools: Data of the present study was collected by using two tools namely; I) Factors Affecting of E-learning Platform Using Questionnaire, II) Nursing Students' Satisfaction Questionnaire. Results: The results showed that highest percent of nursing educators and nursing students had high perception regarding environmental factors and more than one third (37.1%) of nursing students had moderate satisfaction level toward e-learning platform using Conclusion: There was a highly statistically significant relation between factors affecting electronic learning platform using and nursing students' satisfaction. Recommendation: Designing training programs to raise awareness and the ability to use e-learning as an effective training tool.