Benha University

ابراهيم احمد مصطفى احمد عطية

مدرس

كلية الطب البشري الطب الشرعى والسموم الاكلينيكية

Carbon Monoxide induced toxicity: A literature Review of The Challenges in Early Diagnosis of Cardiotoxicity and Neurotoxicity

Benha Journal of Applied Sciences • 2025
العودة
معلومات البحث
المؤلفون Alaa A. Marie* ; Ola G. Hagag; Asmaa Y. Hussein; Ibrahim A. Mostafa
الكلمات المفتاحية Carbon monoxide; H-FABP; Neurogranin; Cardiotoxicity; Neurotoxicity
المجلة العلمية Benha Journal of Applied Sciences
الناشر Benha University
المجلد 10
العدد 5
الصفحات 83-87
publication.type Local
رابط البحث Open Link
المواد المرفقة Not Available
الملخص
odorless and non-irritating but highly toxic gas. It results from incomplete combustion of carbonaceous substances. The current method for CO poisoning begins with clinical suspicion and a review of the patient's medical history. It is then confirmed by detecting elevated CO-Hb levels (greater than 10%), which can be measured through invasive blood gas analysis or non-invasive techniques like multi-wave pulse oximetry. Objective: we summarize recent advances in understanding challenges in early diagnosis of CO induced cardiotoxicity and neurotoxicity.
Cardiac enzymes, ECG, brain computerized tomography scans are essential markers in diagnosis of CO induced cardiotoxicity and neurotoxicity, while heart-type fatty acid-binding protein and neurogranin are emerging as promising biomarkers. Conclusions: Recent markers are needed for early detection of acute in CO induced cardiotoxicity and neurotoxicity other than traditional markers.: we summarize recent advances in understanding challenges in early diagnosis of CO induced cardiotoxicity and neurotoxicity.
Cardiac enzymes, ECG, brain computerized tomography scans are essential markers in diagnosis of CO induced cardiotoxicity and neurotoxicity, while heart-type fatty acid-binding protein and neurogranin are emerging as promising biomarkers. Conclusions: Recent markers are needed for early detection of acute in CO induced cardiotoxicity and neurotoxicity other than traditional markers.
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