Background: Our goal is to study the hematological changes in Covid19 and the relation between these changes and the progression of the
disease. Methods: It combined a retrospective and prospective study at
the isolation unit of Covid-19 department of Benha Children Hospital.
The time frame for this research was from January of 2021 through
December of the same year. All patients diagnosed with COVID-19 or
Multisystem inflammatory syndrome in children (MIS-C) /Kawasaki,
were included in the study. Results: This study included 300 patients
who were divided into two groups based on their PCR results. Group I:
negative PCR group (223 patients). Group II: positive PCR group (77
patients). Mean age was statistically significantly higher among negative
COVID 19 group than positive group (p=0.03). Mean HB and HCT %
were statistically significantly higher among negative COVID 19 group
than positive group (p=0.02 and 0.03 respectively), Mean D-dimmer, Sferritin and L D H were statistically significantly higher among positive
COVID 19 group than negative group (p