محمد شوقى السيد صالح البرعى
أستاذ متفرغ
STUDY OF IRON STATUS PARAMETERS AND SERUM ALUMINUM LEVEL IN PATIENTS WITH CHRONIC RENAL FAILURE .EFFECT OF RECOMBINANT HUMAN ERYTHROPOIETN IN AND OTHER MODALITIES OF TREATMENT
BenhaM.J. • 1997
معلومات البحث
المؤلفون
InasEl-ShaarawyMD.MohamedShawkyMD*,SoberAbdEl-RahmanMD,MohamedEl-HendyMDandSherifNigmMD*
الكلمات المفتاحية
Not Available
المجلة العلمية
BenhaM.J.
الناشر
Not Available
المجلد
Vol. 14N02May1997
العدد
Not Available
الصفحات
347-361
publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
Thisstudywasconductedonfifiyuremicpatientsunderregularhaemodialysisand10healthycontrolsubjectsinordertostudytheparametersofironstatusandserumaluminuminthesepatients,andtoellucidatetheefiectofdifferentmodalitiesoftreatmentontheanemia,iron
statusparametersandserumaluminum,
Theuremicpatientswereclassifiedintofivegroups,eachincluded10 i
patients:groupIpatientsdidn'treceivetreatment,group11patientswas
givenTHLLEPO.groupIIIpatientswasgivenoraliron,groupIVpatientsreceivedcorrdvinedEPOandiron,whereasgroupVpatientsreceiveddesferroxamine.Thedurationoftreatmentwas6months.Thefollowinginvestigations, were performed before and after treatment: complete
bloodpicture,bloodurea,serumcreatinine,serumferritin,serumiron,total
ironbindingcapacity,ironbindingsaturation,serumaluminumandbone E
marrow(B.M)biopsy.
Ourstudyshowedthatanemiawasauniversalfindinginalluremic
patients60%hadmicrocytichypochromicand40%hadnormocyticnormochromicanemia.
SerumFe,TIBC,IBSandBMironstorageweresignificantlylowin
uremicpatients,whereasserumferritinandserumaluminumlevelswere
significantlyhighinthesepatients.
statusparametersandserumaluminum,
Theuremicpatientswereclassifiedintofivegroups,eachincluded10 i
patients:groupIpatientsdidn'treceivetreatment,group11patientswas
givenTHLLEPO.groupIIIpatientswasgivenoraliron,groupIVpatientsreceivedcorrdvinedEPOandiron,whereasgroupVpatientsreceiveddesferroxamine.Thedurationoftreatmentwas6months.Thefollowinginvestigations, were performed before and after treatment: complete
bloodpicture,bloodurea,serumcreatinine,serumferritin,serumiron,total
ironbindingcapacity,ironbindingsaturation,serumaluminumandbone E
marrow(B.M)biopsy.
Ourstudyshowedthatanemiawasauniversalfindinginalluremic
patients60%hadmicrocytichypochromicand40%hadnormocyticnormochromicanemia.
SerumFe,TIBC,IBSandBMironstorageweresignificantlylowin
uremicpatients,whereasserumferritinandserumaluminumlevelswere
significantlyhighinthesepatients.