Climate change is a complicated problem and there is an urgent need for climate change adaptation. Cities are the primary drivers of social, economic, and technical progress. Green Cities are cities that show high environmental performance relative to adapting risks derived from climate change while maximizing the economic and social co-benefits. The Authors adopted a data collection strategy to review the issues, and difficulties caused by climate change and how green cities could assist in addressing them, then adopted a case study analysis to analyze the strategies used by Sharm El Sheikh in the transition to green city. The study consequently explored the key factors that support climate change adaptation, which are CO2 emissions, energy, buildings, land use, transport, water and sanitation, waste management, air quality, and environmental governance. It concluded with a set of guidelines that recommends using the potential of green cities as a tool for adapting to climate change challenges.