endemic countries involving Egypt. Vaccination was the only approach to control the FMD
disease in Egypt. This study was carried out for investigation and identification of vaccination
by governorate and prevailing local vaccines in cattle sera in Monofeia governorate during the
period from October 2018 to May 2019. 130 serum samples were tested for FMDV. 30 samples
were used as control, 50 samples collected from animals received local governorate vaccine
and 50 samples from animals received local prevailing vaccine. 49 out of 130 serum samples
(37.7%) were positive and 81 out of 130 serum samples (62.3%) were negative for NSP
(nonstructural protein). Results were (0.0), 3(3.7%) pre-vaccination and 27 (33.33%),
18(22.22%) 1st MPV- 25(30.86%), 18 (22.22%) 2nd MPV-15 (18.52%), 13 (16.05%) 3rd MPV
and (0.0), 9 (11.11%) 4th MPV for serotype A. For serotype (O): 9 (11.1%), 10 (12.4%) pre
vaccination- 36 (44.44%), 28 (34.56%) 1st MPV-33(40.74%), 27 (33.33%) 2nd MPV
24(29.63%), 20(24.7%) 3rd MPV-14(17.3%), 12 (14.80%) 4th MPV. For serotype (SAT2): 4
(4.9%), 24 (4.93%) pre-vaccination-30 (37.03%), 21 (25.93%) 1st MPV-27(33.33%), 21
(25.93%) 2nd MPV- 18 (22.22%), 14(17.3%) 3rd MPV-3 (3.71%), 4 (4.93%) 4th MPV. In
Conclusion. FMD controlling requires vaccines that will supply disparity of infected from vaccinated animals.