Liver transplantation is a life-saving surgery includes removing a diseased or injured liver from patient, called recipient and replace it with a donated whole or partial healthy liver from another person, called a donor. Aim of the study: to evaluate the effect of patients (recipients) educational strategy on their health outcomes post-liver transplantation .Research design: Quasi experimental research design was used. Setting: The study was conducted in Liver Transplantation Unit of National Liver Institute, Menoufia University, Egypt. Sample: A purposive sample of patients who attended the previously mentioned unit through 12 months (n= 55). Tools: three tools were used; (1) The General Data Questionnaire (2) Recipients' Learning needs Assessment (3) Recipients health outcomes .Results: shows the mean score of total information was 13.82 ± 2.35 pre educational strategy implementation which improved to 41.56 ± 6.26 and 41.24 ± 7.56 immediate post and at discharge respectively , there was an improvement in the total mean score practice 13.85 ± 17.21 from pre implementing educational strategy , to 41.55 ± 6.63 and 48.47 ± 5.76 immediate post implementing educational strategy and at disgharge ,respectively. Also there was statistically significant improvement inpatients' health outcomes post educational strategy implementation at p