Amal Fathy Soliman Mostafa
Professor
Significance of Anti-C1q Antibodies in Patients with Systemic Lupus Erythematosus as A Marker of Disease Activity and Lupus Nephritis
THE EGYPTIAN JOURNAL OF IMMUNOLOGY • 2016
Publication Information
Authors
1Amal F Soliman, 1Sami EL-Said Egailla, 2Eman R Abdel Gawad, 2Amira I Mansour,3Tohamy H ElKhouly,1Marwa YA Mahgoub
Keywords
Anti-C1q Antibodies Systemic Lupus Erythematosus Disease Activity Lupus Nephritis
Journal
THE EGYPTIAN JOURNAL OF IMMUNOLOGY
Publisher
Not Available
Volume
23
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Anti-C1q autoantibodies have been proposed as a useful marker in SLE. This study aimed at measuring serum levels of anti-C1q antibodies in patients with SLE and investigates correlations of this level with the histopathological classes of renal biopsies and disease activity. The anti-C1q antibody level was measured in 30 females SLE patients and 20 controls. The activity of SLE disease was calculated according to the SLE disease activity index. A renal biopsy from patients with clinical manifestations of renal disease was obtained. There was a significant increase in the level of anti-C1q antibodies in SLE patients than controls and in patients with active LN than inactive LN (P