Background: Cervical cancer a significant health issue worldwide. Improving women hope level has a
pivotal role in reducing fatigue and improve quality of life Aim: This research aimed to evaluate effect of
nursing model based on Snyder’s hope theory on fatigue and quality of life among women with cervical
cancer Design: A quasi-experimental research (two groups pre/posttest design). Sample: 54 women
diagnosed with cervical cancer. Setting: The present research conducted at obstetric & gynecological
department at Helwan General Hospital, Egypt. Tools: Four tools were used for data collection: A structured
interviewing questionnaire, Herth hope index, Cancer-related fatigue scale and Functional Assessment of
Cancer Therapy- General. Results: There was no a statistical significant difference in the mean scores of
the Herth Hope Index, Cancer-related fatigue and Quality of life between the study and control groups at pre
intervention phase (p ˃ 0.05). However, after three and six months of intervention, the mean score of the
Herth Hope Index, Cancer-related fatigue and Quality of life were higher among study group than the control
group with highly statistical significant difference (p ≤ 0.001). Conclusion: Application of nursing model
based on Snyder's hope theory was effective in improving level of knowledge, reducing level of fatigue and
improving quality of life among woman with cervical cancer. Recommendation: All women diagnosed with
cervical cancer should receive printed booklets and brochures containing component of Snyder's hope
theory and how to apply it. These booklets should be kept in all obstetrics and gynecological units.