Benha University

Mohamed Abdel_rahman Alhefnawy

Asst. Professor

Faculty of Medicine UROLOGY

Microsurgical Denervation of the Penis for Lifelong Premature Ejaculation: A Prospective Multicenter Study Evaluating Technique Modification and Early Clinical Outcomes

Urology • 2026
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Publication Information
Authors K Almekaty ; M Alhefnawy ; A Ismael ; A Elabd ; A Rashed ; M Ragab ; M H Zahran.
Keywords Not Available
Journal Urology
Publisher Elsevier
Volume Not Available
Issue Not Available
Pages Not Available
publication.type International
Paper Link Open Link
Supplementary Materials Not Available
Abstract
Objective
To prospectively assess the clinical outcomes and safety of microsurgical denervation of the penis (MSDP) for treatment of lifelong premature ejaculation (LPE); and to examine the impact of transitioning from partial to more extensive denervation.
Methods
A prospective multicenter study including 60 men with LPE unresponsive to optimized medical treatment who underwent MSDP. The primary outcome was to assess changes in Intravaginal Ejaculatory Latency Time (IELT), Premature Ejaculation Profile (PEP), Patients' and Partners’ Satisfaction scores at 1, 3, and 6 months after MSDP. The secondary outcome was to evaluate the effect of added-on medical treatment to patients who underwent MSDP without satisfactory results after 6 months.
Results
MSDP was associated with statistically significant increases in the mean± SD IELT [from 5.4±0.3 to 77±22, 127±35, and 125±37, p
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