Mohamed Mohamedy Ghanem
Dept. Head
lecithin cholesterol acyltransferase (LCAT) activity as a predictor for ketosis and parturient haemoglobinuria in Egyptian water buffaloes. Research in Veterinary Science. DOI: 10.1016/j.rvsc.2009.07.00
• 2010
Publication Information
Authors
Mohamed M. Ghanem and Wael M. El-Deep
Keywords
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publication.type
International
Paper Link
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Supplementary Materials
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Abstract
Lecithin cholesterol acyltransferase (LCAT) activity was measured in 48 Egyptian water buffaloes four
weeks pre-parturient. The activity was significantly low in 37 buffaloes (77.1%). Four weeks post-partum,
clinical examination revealed that 23 buffaloes had the clinical signs of ketosis (K) while 14 had the clinical
signs of parturient-haemoglobinuria (PHU). Serum samples were collected from 5 buffaloes of each
group (K and PHU) besides 5 clinically healthy buffaloes with normal LCAT (control). Glucose level was
significantly reduced in K and PHU groups while the phosphorous (P) level was significantly reduced
in PHU group compared to control. There were significant reductions in the total cholesterol, free cholesterol,
triglycerides, total protein and albumin in K and PHU groups; whereas, significant increases in AST,
GGT, non-esterified fatty acids (NEFA) and beta-hydroxybutyric acid (BHBA) in K and PHU groups were
detected. Therefore, LCAT could be a predictor for metabolic disorders in Egyptian water buffaloes.
2009 Elsevier Ltd. All rights reserved.
weeks pre-parturient. The activity was significantly low in 37 buffaloes (77.1%). Four weeks post-partum,
clinical examination revealed that 23 buffaloes had the clinical signs of ketosis (K) while 14 had the clinical
signs of parturient-haemoglobinuria (PHU). Serum samples were collected from 5 buffaloes of each
group (K and PHU) besides 5 clinically healthy buffaloes with normal LCAT (control). Glucose level was
significantly reduced in K and PHU groups while the phosphorous (P) level was significantly reduced
in PHU group compared to control. There were significant reductions in the total cholesterol, free cholesterol,
triglycerides, total protein and albumin in K and PHU groups; whereas, significant increases in AST,
GGT, non-esterified fatty acids (NEFA) and beta-hydroxybutyric acid (BHBA) in K and PHU groups were
detected. Therefore, LCAT could be a predictor for metabolic disorders in Egyptian water buffaloes.
2009 Elsevier Ltd. All rights reserved.