Mohamed Eltantawy IbrahIm
Professor
Association of Pre- and Post- dialysis Uric Acid Difference to Left Ventricular Structural and Functional Disorders in Maintenance Hemodialysis Patients
Benha medical journal • 2023
Publication Information
Authors
Mohamed E. Ibrahim, El-Metwally L. El-Shahawy, Ayman M. Elbadwy, Samar A. Omran, Saddam A. Hassan, Shereen M.Ahmed
Keywords
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Journal
Benha medical journal
Publisher
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Volume
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Issue
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Pages
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publication.type
Local
Paper Link
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Supplementary Materials
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Abstract
Background: The hallmark of gout is hyperuricemia. This substance has ties to cardiovascular disease's pathophysiology, which is the main killer
of dialysis patients. Diabetes, insulin resistance, and other cardiovascular diseases as well as hypertension are all linked to hyperuricemia. Death from any cause is prevented by high SUA levels. Smaller studies found Jshaped relationships between SUA and all-cause mortality. In line with its function in protein metabolism, a recent study suggests that SUA
could be used as a nutritional status indicator in hemodialysis patients.
Rather than a high SUA, a superior nutritional state may explain survival connections. In HD patients, LVH with diverse etiologies is predictive of
CV mortality and morbidity. Aim: to investigate the relationship between left ventricular morphological and functional problems and preand post-dialysis uric acid differences in individuals receiving
maintenance hemodialysis. Subject and Methods: This study was
carried out on ESRD patients in Internal Medicine Department of Benha
University in the hemodialysis unit, where 100 patients were selected.
Results: There were high statistically significant differences between the
studied patients systolic and diastolic blood pressure before and after
hemodialysis. There were high statistically significant differences
between the studied patient’s serum level of uric acid, creatinine and urea before and after
hemodialysis. Conclusion: This study found a strong relationship between uric acid and both LV
parameters and ejection fraction. We discovered through regression analysis that serum uric acid was
an important indicator of LV ejection fraction
of dialysis patients. Diabetes, insulin resistance, and other cardiovascular diseases as well as hypertension are all linked to hyperuricemia. Death from any cause is prevented by high SUA levels. Smaller studies found Jshaped relationships between SUA and all-cause mortality. In line with its function in protein metabolism, a recent study suggests that SUA
could be used as a nutritional status indicator in hemodialysis patients.
Rather than a high SUA, a superior nutritional state may explain survival connections. In HD patients, LVH with diverse etiologies is predictive of
CV mortality and morbidity. Aim: to investigate the relationship between left ventricular morphological and functional problems and preand post-dialysis uric acid differences in individuals receiving
maintenance hemodialysis. Subject and Methods: This study was
carried out on ESRD patients in Internal Medicine Department of Benha
University in the hemodialysis unit, where 100 patients were selected.
Results: There were high statistically significant differences between the
studied patients systolic and diastolic blood pressure before and after
hemodialysis. There were high statistically significant differences
between the studied patient’s serum level of uric acid, creatinine and urea before and after
hemodialysis. Conclusion: This study found a strong relationship between uric acid and both LV
parameters and ejection fraction. We discovered through regression analysis that serum uric acid was
an important indicator of LV ejection fraction