Nehad Ahmed Foad
Professor
• Serum Level of Growth Arrest–Specific 6 (Gas6) Protein and Genetic Variations in the Gas6 Gene in Patients with Type 2 Diabetes Mellitus. .
the Egyptian Journal of Immunology, • 2015
Publication Information
Authors
Nehad A Fouad, Sheref M Eltaher, Omminea A Abdullah, Ramy A Metwally
Keywords
Not Available
Journal
the Egyptian Journal of Immunology,
Publisher
Not Available
Volume
22
Issue
1
Pages
41-47
publication.type
International
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Growth arrest-specific protein 6 (Gas6) belongs to a family of vitamin K-dependent coagulation proteins. Plasma levels of Gas6 are associated to altered glucose tolerance. This study aimed at determining whether c.843+7G>A Gas6 polymorphism is associated with the development of type 2 diabetes mellitus. The study included 05 patients with type 2 diabetes and 40 matched controls. The Gas6 protein was measured in serum using ELISA and Gas6 gene polymorphism by polymerase chain reaction- Restriction Fragment Length Polymorphism. The GG genotype was the most prevalent in the diabetic patient. The frequency of A allele in the diabetic group was lower than the control group (P