Background: Chronic gastritis is a common gastrointestinal disorder characterized by
persistent inflammation of the gastric mucosa, which can significantly affect patients’ quality of
life. Poor compliance with treatment regimens, including medication adherence, dietary
modifications, and lifestyle changes, remains a major challenge in managing the disease and
preventing complications. Educational programs play a vital role in improving patients’ knowledge
and promoting adherence to therapeutic recommendations, which may enhance health outcomes and
reduce disease burden. The aim of the study: was to evaluate the effect of educational program on
compliance of patients with chronic gastritis. Study design: Quasi-experimental research design
(pre/post) will be utilized to achieve the aim of the study. Setting: The study was conducted in
medical departments at Benha University Hospital, to be continued in medical outpatient clinic for
follow up. Subjects: A Purposive sample of (112) patients with chronic gastritis. Tools: Two tools
were used; tool (I): Patients' Knowledge assessment questionnaire, it involved the patients' personal
data, medical history and patients' knowledge assessment. Tool (II): Patients’ compliance scale, it
involved three domains; diet, exercise, medication follow up compliance . Results: there was
statistically significant differences in total knowledge levels between pre and post educational
program implementation periods (p value=