Background : The aim of this study is to assess and compare between the efficacy of continuous Para scapular sub iliocostalis plane block and epidural catheter in adult patients scheduled for elective thoracotomy surgery in order to decrease the incidence of post thoracotomy pain syndrome. Methods: We conducted a single-center prospective observational study involving patient undergoing thoracotomy operation. The patients were divided into two groups ,thoracic epidural group and par scapular sub iliocostalis group ,then they were evaluated postoperatively for 48 hrs. for pain severity( VAS) , hemodynamics ,need for supplemental analgesia .Results: In this study 62 patients were screened for eligibility, 10 patients of them were excluded from the study. Regarding VAS scores obtained (VAS) in both groups which monitored at 0 time (on arrival to ICU), then every 6 hours for 48 hour postoperative, we found that there was no significant difference between both groups. Regarding incidence of hemodynamic changes due to the block, there was significant difference between both groups. We recorded hypotension (systolic pressure