Marwa Awade Abdelghany Ibrahim Saleh
Asst. Lecturer
The Efficacy of Alcoholic Extracts of Morus Macroura (Mulberries), Lepidium Sativum (Garden Cress Seeds) and Diclazuril Against E. stiedae in Experimentally Infected Rabbits
International Journal of Veterinary Science • 2023
Publication Information
Authors
Marwa Saleh1*, Mohamed Ramadan1, Reham Elmadawy1, Mai Morsi2 and Lubna El-Akabawy1
Keywords
Coccidiosis, Morus macroura, Lepidium sativum, Alcoholic extract.
Journal
International Journal of Veterinary Science
Publisher
Not Available
Volume
12(6): 869-878
Issue
12(6): 869-878
Pages
12(6): 869-878
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
The current study aimed to assess the protective role of Morus Macroura (Mulberries), Lepidium Sativum (Garden
Cress Seeds) against E. stiedae in experimentally infected rabbits. Fifty rabbits were randomly divided into five
groups: G1 and G2 rabbits were supplemented with M. Macroura and L. sativum; respectively with a daily dose of
300mg/kg BW which began one week before infection and continued daily till the end of the experiment. G3 was
administered diclazuril (1ppm) for only one week before infection; G4 was kept as infected- non-treated (CP) and G5
was kept as untreated- uninfected (CN). On 7th day of the experiment, all groups except G5 were orally infected with
104 sporulated oocysts of E. stiedae using a stomach tube. The following up of the clinical symptoms, weight, fecal
oocysts count, hematological and biochemical parameters (liver, and kidney function) were done for each rabbit
throughout the experiment, in addition the lesion score was done after PM examination and histopathology of the
liver. The results revealed a significant improvement in clinical signs in botanical plant and diclazuril treated groups,
with an improvement in body weight, a highly significant reduction in oocysts shedding with a significant
improvement of CBC and liver and kidney enzymes compared to CP group. In conclusion, both M. Macroura and L.
Sativum could equally compete with the chemical drug (Diclazuril) in their anti-coccidial effect on E. stiedae and can
be used as a safe useful alternative remedy to control rabbit coccidiosis.
Cress Seeds) against E. stiedae in experimentally infected rabbits. Fifty rabbits were randomly divided into five
groups: G1 and G2 rabbits were supplemented with M. Macroura and L. sativum; respectively with a daily dose of
300mg/kg BW which began one week before infection and continued daily till the end of the experiment. G3 was
administered diclazuril (1ppm) for only one week before infection; G4 was kept as infected- non-treated (CP) and G5
was kept as untreated- uninfected (CN). On 7th day of the experiment, all groups except G5 were orally infected with
104 sporulated oocysts of E. stiedae using a stomach tube. The following up of the clinical symptoms, weight, fecal
oocysts count, hematological and biochemical parameters (liver, and kidney function) were done for each rabbit
throughout the experiment, in addition the lesion score was done after PM examination and histopathology of the
liver. The results revealed a significant improvement in clinical signs in botanical plant and diclazuril treated groups,
with an improvement in body weight, a highly significant reduction in oocysts shedding with a significant
improvement of CBC and liver and kidney enzymes compared to CP group. In conclusion, both M. Macroura and L.
Sativum could equally compete with the chemical drug (Diclazuril) in their anti-coccidial effect on E. stiedae and can
be used as a safe useful alternative remedy to control rabbit coccidiosis.