Arwa Elsayed Amer
Asst. Professor
Hematological indices in psoriatic enthesopathy: relation to clinical and ultrasound evaluation
Clinical Rheumatology • 2024
Publication Information
Authors
Arwa S. Amer1 · Ahmed Y. Al Shambaky1
· Seham G. Ameen2
· Amira Khalil Sobih
Keywords
Not Available
Journal
Clinical Rheumatology
Publisher
Springer
Volume
Not Available
Issue
Not Available
Pages
Not Available
publication.type
International
Paper Link
Open Link
Supplementary Materials
Not Available
Abstract
Background Enthesopathy is considered a crucial aspect of assessment and outcome in psoriatic arthritis (PsA). Musculoskeletal ultrasound (MSUS) is a critical tool for accurately detecting enthesitis. Recent research focuses on identifying
simple biomarkers for detecting and monitoring psoriatic enthesopathy. Red cell distribution width (RDW), mean platelet
volume (MPV), and neutrophil/lymphocyte ratio (NLR) are components of a complete blood count (CBC) and are reliable
bio-infammatory markers in various rheumatic diseases.
Aim of work To measure MPV, RDW, and NLR in psoriatic enthesopathy and determine their relationship to disease activity
and MSUS fndings.
Patients and methods This study focused on 30 people with psoriatic arthritis (PsA) as per CASPAR criteria, along with
20 control subjects. Enthesopathy was evaluated clinically using the Leeds Enthesitis Index (LEI). The modifed Disease
Activity Index of Psoriatic Arthritis (DAPSA28) was calculated, and RDW, MPV, NLR, CRP, and ESR were measured.
Each enthesis in LEI was radiologically assessed using plain radiography and MSUS according to OMERACT defnitions.
Results There was a signifcant relationship between clinical tenderness, the presence of enthesophytes on plain radiography,
and MSUS fndings at entheses sites (p
simple biomarkers for detecting and monitoring psoriatic enthesopathy. Red cell distribution width (RDW), mean platelet
volume (MPV), and neutrophil/lymphocyte ratio (NLR) are components of a complete blood count (CBC) and are reliable
bio-infammatory markers in various rheumatic diseases.
Aim of work To measure MPV, RDW, and NLR in psoriatic enthesopathy and determine their relationship to disease activity
and MSUS fndings.
Patients and methods This study focused on 30 people with psoriatic arthritis (PsA) as per CASPAR criteria, along with
20 control subjects. Enthesopathy was evaluated clinically using the Leeds Enthesitis Index (LEI). The modifed Disease
Activity Index of Psoriatic Arthritis (DAPSA28) was calculated, and RDW, MPV, NLR, CRP, and ESR were measured.
Each enthesis in LEI was radiologically assessed using plain radiography and MSUS according to OMERACT defnitions.
Results There was a signifcant relationship between clinical tenderness, the presence of enthesophytes on plain radiography,
and MSUS fndings at entheses sites (p