Abstract: Adolescents often encounter dysmenorrhea, which is a common issue that
greatly affects the quality of life for females. A beneficial approach to alleviate
dysmenorrhea is through William's Flexion Exercise. This technique is considered one
of the most efficient complementary therapies due to its affordability and absence of
adverse effects Purpose :to evaluate the effect of William's flexion exercise on
menstrual pain, depression and sleep quality among female nursing students with
primary dysmenorrhea. Design: A quasi experimental design (One-Group, Time series
quasi-experimental design). Setting: The research was conducted at the Faculty of
Nursing, Benha University. Sample: A purposive sample of 76 female nursing students.
Instruments: Five instruments were used: A structured self-administered questionnaire,
Numeric pain rating scale, Patient health questionnaire-9 and Pittsburgh sleep quality
index. Results: There was a statistical significant improvement in female nursing
students' total knowledge score regarding dysmenorrhea at 4 weeks and 8 weeks post
intervention compared to pre-intervention. As well as, there was a statistical significant
improvement in total mean scores of the pain severity, depression level and quality of
sleep among female nursing students at 4 weeks and 8 weeks post-intervention
compared to pre-intervention. Conclusion: The implementation of William' flexion
exercise was effective in reducing level of menstrual pain, depression level and
improving quality of sleep among female nursing students with primary dysmenorrhea.
Recommendation: It was recommended that William' flexion exercises should be
incorporated into as a complementary and alternative therapy into nursing education and
curriculum as a method for relieving primary dysmenorrhea.