Hany sayed ahmed Bauiomy
Asst. Professor
Pregabalin as Alternative to Epidural Blood Patch in Treatment of Post dural Puncture Headache: A Randomized Controlled Clinical Trial
Benha medical journal • 2024
Publication Information
Authors
Nahed Fouad Abo-Elmaety; Neveen Kohaf; Hany Bauiomy*; Ahmed Abosakaya
Keywords
Not Available
Journal
Benha medical journal
Publisher
Benha medical journal
Volume
41
Issue
5
Pages
323-336
publication.type
Local
Paper Link
Not Available
Supplementary Materials
Not Available
Abstract
Background and Aims: Post dural puncture headache (PDPH) commonly arises following a lumbar puncture. It is typically managed through conservative measures or an epidural blood patch (EBP), but each has limitations. This trial aimed to compare the efficacy and safety of pregabalin versus EBP in the management of PDPH.
Methods: This randomized controlled trial was conducted on 75 cases with confirmed diagnosis of PDPH. Patients were equally randomized into three groups: Group A (pregabalin group) received oral pregabalin treatment administered at 150 mg daily, with 75 mg given every 12 hours. Group B (EBP group) received EBP and Group C (control group) received conservative treatment.
Results: Complete relief of headache was experienced by 13 (52%) patients in group A, 18 (72%) patients in group B, and 5 (20%) patients in group C, with significant distinctions observed among the examined groups (P
Methods: This randomized controlled trial was conducted on 75 cases with confirmed diagnosis of PDPH. Patients were equally randomized into three groups: Group A (pregabalin group) received oral pregabalin treatment administered at 150 mg daily, with 75 mg given every 12 hours. Group B (EBP group) received EBP and Group C (control group) received conservative treatment.
Results: Complete relief of headache was experienced by 13 (52%) patients in group A, 18 (72%) patients in group B, and 5 (20%) patients in group C, with significant distinctions observed among the examined groups (P