Background: Hyperemesis gravidarum is often defined as intractable nausea and vomiting
during pregnancy. Hyperemesis gravidarum is severe enough to affect the general condition of the
pregnant women and may require hospitalization. Aim: The research aimed to investigate the
effectiveness of tailored education program on pregnant women's knowledge and practices regarding
hyperemesis gravidarum and on its severity. Design: A quasi-experimental research (one group
pre/post-test) design was adopted to fulfil the research aim. Setting: the research was conducted at
Obstetrics and Gynecology Department (high-risk pregnancy ward) and at antenatal outpatient clinics
at three hospitals (Benha University Hospitals, Benha Teaching Hospital and Benha Health Insurance
Hospital). Sample: A purposive sample of 120 pregnant women. Tools: Four tools were used for
data collection; a structured interviewing questionnaire, women' knowledge assessment sheet,
women' health practices assessment sheet and Modified 24-hour Pregnancy-Unique Quantification
of Emesis questionnaire. Results: showed a highly statistically significant improvement concerning
pregnant women's knowledge and healthy practices regarding hyperemesis gravidarum at post
intervention phase compared to pre- intervention phase (P≤ 0.001). There was a statistical significant
reduction in the severity of hyperemesis gravidarum at post-intervention phase compared to pre-
intervention phase (p≤ 0.05).