Manzala Lake, the largest natural freshwater body in Egypt, is situated in the northeastern part of the Nile Delta. It faces major environmental challenges, largely due to pollution from untreated industrial effluents, sewage, and agricultural runoff. As part of Egypt's national initiative to rehabilitate its lakes, a development project was launched in 2017 and concluded in June 2022. The project aimed to purify the lake by eliminating contaminants, clearing invasive vegetation, deepening the canals, the study focuses on assessing land cover changes using remote sensing and GIS, and offers some recommendations for sustainable lake use following the development efforts. The findings aim to equip policymakers and urban planners with crucial insights to harmonize environmental protection with sustainable development goals.