Benha University

Rasha Mohamed Mohamed Zakaria Radwan

Lecturer

Faculty of Medicine PEDIATRICS

Hypothermia on admission and its association with neonatal mortality and morbidity in neonatal intensive care unit

• 2023
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Publication Information
Authors M.A. Mostafaa, O.M. AbdelHaiea, S.A. Abdelmegiudb, B.K.M. Lasheena and R.M. Zakariaa,∗
Keywords Not Available
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publication.type International
Paper Link Not Available
Supplementary Materials Not Available
Abstract
BACKGROUND: Neonatal hypothermia is a drop in the newborn’s core temperature less than 36.5◦C. It is crucial in
neonatal morbidity and mortality, particularly in preterm infants. This research aimed to assess the incidence and risk factors
of neonatal hypothermia and its effect on neonatal mortality and short-term morbidity during Neonatal Intensive Care Unit
(NICU) admission.
METHODS: This observational study was conducted on all neonates admitted to the NICU at Benha University Hospital.
The core temperature was measured on admission for all admitted neonates and were followed up to assess the impact of
hypothermia on short-term outcomes and mortality.
RESULTS: A total of 323 neonates were admitted to the NICU throughout the research period. Thirty-five cases were
excluded due to congenital anomalies or missing or late admission temperature recordings. The study included 288 neonates
whose mean gestational age was 34.6±3.4 weeks, and their mean birth weight was 2.35±0.9 kg. Two-thirds (66%) of the
neonates had core temperatures indicating hypothermia (axillary temperature of less than 36.5◦C), one-third (33%) were
normothermic, and only three (1%) were hyperthermic. Neonates with hypothermia had statistically lower gestational age,
higher frequency of multiple births, prolonged need for respiratory support, higher rates of pulmonary hemorrhage, sepsis,
intraventricular hemorrhage (IVH), and necrotizing enterocolitis, longer hospital stay, and mortality.
CONCLUSIONS: There is a high incidence of neonatal hypothermia at NICU admission. Lower gestational age, increased
multiples, lower APGAR score, lower birth weight, and lack of antenatal steroids were significantly associated with hypothermia
at NICU admission. Hypothermia was found to be a significant factor contributing to increased mortality and morbidity
rates in affected neonates
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