Background: Breast cancer is currently the highest-ranking cancer in the world in terms of morbidity and mortality among women. This study aimed to to evaluate Platelet to lymphocyte ratio as a prognostic marker in early breast cancer. Assessing the prognostic and predictive values of this relationship. Methods: This cross-sectional study included 100 female patients with breast cancer presented to Hemato-Oncology Unit, Benha University Hospitals. Patients were divided into equal groups regarding PLR : Group I (n=57): High PLR >150. Group II (n=43): Low PLR