Vitiligo is a widespread skin condition described by immune-mediated
destruction of melanocytes, which has a negative impact on quality of life and increased
patients’ stigmatization. Aim: This study aimed to evaluate the effect of applying Roy’s
adaptation model on quality of life for patients with vitiligo. Research design: A quasi-
experimental design was used. Setting: The study was conducted at Dermatology and
Leprosy Clinics in Benha City, Egypt. Sample: A purposive sample included 146 vitiligo
patients and equally separated into two groups (study 73 patients and control 73 patients).
Tools: Three tools were used, I: An interviewing questionnaire consisted of three parts,
patients’ demographic characteristics, patients’ past and present medical history and
patients’ knowledge regarding vitiligo. II: Dermatology life quality index questionnaire
to assess quality of life for vitiligo patients. III: Roy’s adaptation model to assess vitiligo
patients’ adaptive behavior. Results: The present study revealed that all studied patients
complained of skin whitening, had affected face and were feeling embarrassed from
society’s view. There was a significant improvement in the total levels of study group’
knowledge, quality of life and adaptive behavior post one and three months of Roy’s
adaptation model implementation compared with control group. Also, dermatology life
quality score post Roy's Adaptation model implementation was best predicted among
study group by age, marital status, total knowledge and total adaptive behavior
respectively and among control group by marital status, occupation, monthly income, and
total adaptive behavior respectively.