Sarah Abdalla goda Radwan
Lecturer
Predictive role of CHA₂DS₂-VASc score in acute coronary syndrome patients and value of adding global longitudinal strain to CHA₂DS₂-VASc score
• 2025
Publication Information
Authors
Hager Allam * , Shaimaa Mostafa, El-Sayed Abd Khalek, Sara Abdalla
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publication.type
Local
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Abstract
Background: Future clinical management would be improved by accurate and early identification of ACS patients
at high CV risk. In non-valvular atrial fibrillation patients, the prognostic risk of thromboembolism has been
evaluated using CHA₂DS₂-VASc scores. It has recently been shown to assess the severity of CAD and foresee
patient outcomes. Also, LV global longitudinal strain is an independent predictor of outcome. Our study aimed
to determine the added value of LV longitudinal strain (GLS) to CHA₂DS₂-VASc in predicting the outcome and
severity of CAD in patients with acute coronary syndrome (ACS).
Methods: A total of 577 patients with primary diagnosis of ACS were included between January and July 2021.
All patients had evaluations based on history, clinical examination, 12-lead ECG, TTE, and coronary angiography. Six months follow-up had been provided to all patients.
Results: Syntax score was significantly higher among patients with high-risk CHA₂DS₂-VASc score (30.5 ± 6.1 vs.
17.34 ± 8.7 vs. 11.11 ± 8.2), p-value
at high CV risk. In non-valvular atrial fibrillation patients, the prognostic risk of thromboembolism has been
evaluated using CHA₂DS₂-VASc scores. It has recently been shown to assess the severity of CAD and foresee
patient outcomes. Also, LV global longitudinal strain is an independent predictor of outcome. Our study aimed
to determine the added value of LV longitudinal strain (GLS) to CHA₂DS₂-VASc in predicting the outcome and
severity of CAD in patients with acute coronary syndrome (ACS).
Methods: A total of 577 patients with primary diagnosis of ACS were included between January and July 2021.
All patients had evaluations based on history, clinical examination, 12-lead ECG, TTE, and coronary angiography. Six months follow-up had been provided to all patients.
Results: Syntax score was significantly higher among patients with high-risk CHA₂DS₂-VASc score (30.5 ± 6.1 vs.
17.34 ± 8.7 vs. 11.11 ± 8.2), p-value