Hemorrhoids (also known as ‘piles’) are swollen varicose veins located around the anus. Hemorrhoids are a common condition in pregnancy. The main reported symptoms caused by hemorrhoids are burning, itching, perianal pain, and bleeding Aim: The study aimed to assess the effect of nursing guidelines on hemorrhoids symptoms among pregnant women. Design: A Quasi experimental design was used for conducting the study. Setting: The study was conducted in the obstetrics and gynecology antenatal outpatient clinic at Benha University Hospital. Sample: A purposive sample of 120 pregnant women divided to 2 equal groups study group and control group were selected according to inclusion criteria. Tools: two tools were utilized for data collection 1) A structured interviewing questionnaire 2) The Colorectal Evaluation of Clinical Therapeutics Scale. Results of this study showed that knowledge and healthy practices there was insignificant relation between study and control groups pre intervention