Yasser mohammed hassan mandour
Professor
Effect of hot saline pack versus topical tranexamic acid in post adenoidectomy bleeding
• 2023
Publication Information
Authors
Yasser Mohammed Hassan Mandour, Ahmed Ashraf Salah El Hamshary, Mohsen Mahmoud Abd Elrazeq,
Omnia Abd Elrahman Elbosraty* and Mostafa Gomaa Sobhy
Keywords
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publication.type
Local
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Abstract
Background Adenoidectomy is a popular surgical technique in the field of otolaryngology that is successful, safe,
and effective. Diffuse microvascular post-adenoidectomy bleeding, on the other hand, is still a common concern.
Aim The objective of this study is to do a comparison between the efficacy of a hot saline pack versus topical
tranexamic acid when administered topically in children who have had only adenoidectomy in terms of intra-operative
blood loss and post-operative bleeding.
Methods This prospective case-control study contained a total of 180 patients, divided into three classes. Class A:
This included 60 patients with application of a hot saline pack in control of intra-operative adenoidectomy bleeding.
Class B: This included 60 patients with application of a topical tranexamic acid pack in control of intra-operative
adenoidectomy bleeding. Class C: This included 60 patients with the use of a pack to hold intra-operative adenoidectomy
bleeding
Results The mean intraoperative blood loss in class B was lower than classes A and C, the mean pre- and post-operative
HB level was lower in class C than in classes A and B, the difference was statistically considerable between the
three classes, comparison between classes showed statistically considerable differences between classes A and C and
also between classes B and C, while there was a statistically non-considerable difference between classes A and B.
Conclusion The current study found that a topical tranexamic acid pack was more effective for post-adenoidectomy
haemostasis than a hot saline pack, with a shorter time to haemostasis and fewer recurettage and electrocauterization
procedures.
Trial registration Name of registration trial: Research ethics committee faculty of medicine Benha university. Registration
number: Ms1-1-2020. Date of registration: 22-1-2021.
and effective. Diffuse microvascular post-adenoidectomy bleeding, on the other hand, is still a common concern.
Aim The objective of this study is to do a comparison between the efficacy of a hot saline pack versus topical
tranexamic acid when administered topically in children who have had only adenoidectomy in terms of intra-operative
blood loss and post-operative bleeding.
Methods This prospective case-control study contained a total of 180 patients, divided into three classes. Class A:
This included 60 patients with application of a hot saline pack in control of intra-operative adenoidectomy bleeding.
Class B: This included 60 patients with application of a topical tranexamic acid pack in control of intra-operative
adenoidectomy bleeding. Class C: This included 60 patients with the use of a pack to hold intra-operative adenoidectomy
bleeding
Results The mean intraoperative blood loss in class B was lower than classes A and C, the mean pre- and post-operative
HB level was lower in class C than in classes A and B, the difference was statistically considerable between the
three classes, comparison between classes showed statistically considerable differences between classes A and C and
also between classes B and C, while there was a statistically non-considerable difference between classes A and B.
Conclusion The current study found that a topical tranexamic acid pack was more effective for post-adenoidectomy
haemostasis than a hot saline pack, with a shorter time to haemostasis and fewer recurettage and electrocauterization
procedures.
Trial registration Name of registration trial: Research ethics committee faculty of medicine Benha university. Registration
number: Ms1-1-2020. Date of registration: 22-1-2021.
