Benha University

أحمد عبد العزيز محمد حسن

مدرس

كلية الطب البشري طب القلب والأوعية الدموية

The early effect of dapagliflozin on diastolic function parameters in patients with mid range and reduced ejection fraction heart failure

• 2024
العودة
معلومات البحث
المؤلفون Ahmed A.Mohammed, Elsayyed A.Eldarky, Ali I.Ateya and Hagar I.Allam
الكلمات المفتاحية Not Available
المجلة العلمية Not Available
الناشر Not Available
المجلد Not Available
العدد Not Available
الصفحات Not Available
publication.type Local
رابط البحث Not Available
المواد المرفقة Not Available
الملخص
Cardiovascular mortality and hospitalisation rates were greatest among heart failure (HF) patients with
reduced ejection fraction (HFrEF) according to clinical trial data. Treatment of heart failure with sodium-glucose
transporter-2 inhibitors (SGLT2i) has recently made significant strides [1]. Even in patients with HFrEF, LV
diastolic dysfunction was a separate predictor of outcome [2]. It is essential to identify structural abnormalities
using echocardiography since they have been linked to prognosis in HF and DM patients [3]. Both diabetic and
non-diabetes patients with HF have had their risk of death and hospital readmission decreased by SGLT2is,
according to large-scale randomised studies and meta-analyses [4]. These are part of the global guidelines for the
treatment of heart failure (HF) at the intermediate assessment level [5]. Some theories suggest that SGLT2is
exerts its cardioprotective effects by reversing cardiac remodelling [6] and restoring systolic and diastolic function
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