يوسف محمد ياسين الجزار
مدرس
Assessment of Doppler Ultrasonography and Hepatocyte MiRNA-122 for the Diagnosis of Acetaminophen-induced Acute Hepatic Injury in Dogs
Egyptian Journal of Veterinary Sciences • 2024
معلومات البحث
المؤلفون
Youssef M. Y. Elgazzar*1, Mohamed M. Ghanem1, Yassein M. Abdel-Raof1, Heba M.
EL-khaiat1, Mahmoud A. Y. Helal1
الكلمات المفتاحية
Acetaminophen, Dogs, Doppler ultrasonography, MiRNA-122, Ultrasound
المجلة العلمية
Egyptian Journal of Veterinary Sciences
الناشر
Not Available
المجلد
56
العدد
12
الصفحات
Not Available
publication.type
International
رابط البحث
Not Available
المواد المرفقة
Not Available
الملخص
HIS study aimed to evaluate the diagnostic value of Doppler ultrasound parameters of the
hepatic artery, portal vein, and interlobar artery as well as the potential use of miRNA-122 for
the diagnosis of acetaminophen-induced acute hepatic injury in dogs. Ten healthy mongrel
dogs were orally administered 200 mg/kg body weight of acetaminophen daily for ten days. Clinical,
Biochemical, Ultrasonographic, and Doppler ultrasonographic examinations were performed for all
dogs on zero day before induction, 3rd day, and the 10th day of induction. The results of the current
study showed that depression, dullness, and jaundice signs appeared in dogs on the 10th day of
induction. Significant increase (P
hepatic artery, portal vein, and interlobar artery as well as the potential use of miRNA-122 for
the diagnosis of acetaminophen-induced acute hepatic injury in dogs. Ten healthy mongrel
dogs were orally administered 200 mg/kg body weight of acetaminophen daily for ten days. Clinical,
Biochemical, Ultrasonographic, and Doppler ultrasonographic examinations were performed for all
dogs on zero day before induction, 3rd day, and the 10th day of induction. The results of the current
study showed that depression, dullness, and jaundice signs appeared in dogs on the 10th day of
induction. Significant increase (P