Benha University

Ahmed kamal Eldein Abbass

Lecturer

Faculty of Medicine OBSTETRIC & GYNECOLOGY

Vitamin D Level in Lean and Obese Polycystic Ovary Syndrome Patient and The Effect of Its Correction

Journal of Obstetrics, Gynecology and Cancer Research • 2025
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Publication Information
Authors Sara Taha Mostafa Hamed, Ahmed Walid Anwar Murad, Samar Ismail, Ahmed Kamal Eldin Abbas
Keywords PCO,Vit D ,
Journal Journal of Obstetrics, Gynecology and Cancer Research
Publisher Iranian Society of Gynecology Oncology (IRSGO)
Volume Not Available
Issue Not Available
Pages e732317
publication.type International
Paper Link Open Link
Supplementary Materials Not Available
Abstract
Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder associated with both reproductive dysfunction and metabolic abnormalities. Emerging evidence links vitamin D deficiency with worsened PCOS manifestations, including insulin resistance and menstrual irregularity. However, few studies have compared these effects between lean and obese PCOS phenotypes.
Objective
To compare baseline serum vitamin D levels between lean and obese PCOS patients and evaluate the impact of vitamin D supplementation on metabolic and reproductive outcomes in both groups.
Methods
A prospective interventional study was conducted on 100 women with PCOS, aged 18–40, diagnosed according to Rotterdam criteria. Participants were divided into two groups: Group A (lean, BMI < 20 kg/m²) and Group B (obese, BMI ≥ 30 kg/m²). All participants received high-dose oral vitamin D …
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