Benha University

Shaimaa Magdy Hussein Abou Youssef

Asst. Professor

Faculty of Medicine CHEST MEDICINE

Study of Renal Impairment in Patients with Obstructive Sleep Apnea Syndrome and Its Relation to the Disease Severity

Benha Medical Journal • 2025
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Publication Information
Authors Shaimaa M Abo Youssef, Ahdaf A Enan, Samar Samy Ayoub, Enas M Mohammed, Rehab E Elsawy
Keywords Renal Impairment, OSA
Journal Benha Medical Journal
Publisher Not Available
Volume Not Available
Issue Not Available
Pages Not Available
publication.type Local
Paper Link Not Available
Supplementary Materials Not Available
Abstract
Background
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder associated with systemic complications, including renal impairment resulting from intermittent hypoxia and sympathetic activity. This study aimed to evaluate renal dysfunction in cases with OSA, investigate its correlation with disease severity, and assess the impact of continuous positive airway pressure (CPAP) therapy on kidney function.
Methods
In this prospective cohort study, 100 participants (80 OSA cases and 20 healthy controls) were enrolled from Benha University Hospital (December 2022 and December 2024). All participants underwent comprehensive clinical evaluation, overnight polysomnography (PSG), renal function testing [serum creatinine, blood urea, estimated glomerular filtration rate (eGFR), urinary albumin-to-creatinine ratio (UACR)], and renal ultrasonography. OSA cases with moderate-to-severe …
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